The IGFBP3 Polyclonal Antibody, Cy3 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to IGFBP3. This antibody recognizes Human, and Rat antigen. The IGFBP3 Polyclonal Antibody, Cy3 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R